Molecular Profiling of Small Intestinal Neuroendocrine Tumours
نویسندگان
چکیده
منابع مشابه
Small Intestinal Neuroendocrine Tumours
Edfeldt, K. 2014. Small Intestinal Neuroendocrine Tumours. Genetic and Epigenetic Studies and Novel Serum Biomarkers. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 975. 51 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8887-1. Small intestinal neuroendocrine tumours (SI-NETs) are rare, hormone producing and proliferate slowly. Patients usual...
متن کاملMelatonin Immunoreactivity in Malignant Small Intestinal Neuroendocrine Tumours
BACKGROUND/AIMS Small intestinal neuroendocrine tumours (SI-NETs) are derived from enterochromaffin cells. After demonstrating melatonin in enterochromaffin cells, we hypothesized that SI-NETs may express and secrete melatonin, which may have an impact on clinical factors and treatment response. METHODS Tumour tissue from 26 patients with SI-NETs, representing paired sections of primary tumou...
متن کاملSmall Intestinal Tumours
Objective. Balloon enteroscopy (BE) and capsule enteroscopy (CE) are enteroscopy methods that allow examination and treatment of the small bowel. Before the CE and BE era, the small intestine was difficult to access for investigation. Small intestinal tumours are infrequent conditions, but about half of them are malignant. Materials and Methods. A total of 303 BEs were performed in 179 patients...
متن کاملMolecular medicine imaging of neuroendocrine tumours
Neuroendocrine tumours (NETs) are a diverse, highly heterogeneous group of neoplasms derived from endocrine cells found in the neural crest. NETs typically display endocrine metabolism and slow growth, while displaying a wide range of presentations and clinical symptoms. Demonstrating typically small lesions, with varying anatomical localisation, diagnosis is typically in the advanced stages of...
متن کاملPD-L1 expression and presence of TILs in small intestinal neuroendocrine tumours
Background The extent of resistance to immune surveillance in patients with well-differentiated (Wd) (grade 1/2) small-intestinal neuroendocrine tumours (Si-NETs) is unknown. Methods Patients diagnosed with Wd Si-NETs (excluding appendix, which are considered to have a different biology to other midgut NETs) were eligible. Tumoural programmed death (PD)-ligand(L) 1 (PD-L1)/PD-L2/PD-1 and tumo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2014
ISSN: 0923-7534
DOI: 10.1093/annonc/mdu345.2